Cushings
 

Cushing's syndrome

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"cushing's" redirects here. For the circulatory reflex, see Cushing reflex. For the related three-part condition, see Cushing's triad.
Cushing's syndrome
Classification and external resources
Cortisol
ICD-10 E24.
ICD-9 255.0
DiseasesDB 3242
MedlinePlus 000410
eMedicine med/485 
MeSH D003480

Cushing's Syndrome (also called hypercortisolism or hyperadrenocorticism) is an endocrine disorder caused by high levels of cortisol in the blood from a variety of causes, including a pituitary adenoma (known as Cushing's disease), adrenal hyperplasia or neoplasia, ectopic adrenocorticotropic hormone (ACTH) production (e.g., from a small cell lung cancer), and iatrogenic (steroid use). Normally, cortisol is released from the adrenal gland in response to ACTH being released from the pituitary gland. Both Cushing's syndrome and Cushing's disease are characterized by elevated levels of cortisol in the blood, but the cause of elevated cortisol differs between the two. Cushing's disease specifically refers to a tumour in the pituitary gland that stimulates excessive release of cortisol from the adrenal gland by releasing large amounts of ACTH. In Cushing's disease, ACTH levels do not respond to negative feedback from the high levels of cortisol.

Cushing's disease was described by American physician, surgeon and endocrinologist Harvey Cushing (1869-1939) and reported by him in 1932.[1]

Cushing's syndrome—which is also a relatively common condition in domestic dogs and horses—is characterised by abnormal fat deposition. (The syndrome in horses leads to weight loss, polyuria and polydipsia and may cause laminitis.) In Cushing's syndrome there is a tumor in the adrenal cortex and low levels of ACTH.

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Live From The Blogosphere!

Cushings Disease
Cushings Disease Articles.

Medical research compilation
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Anyone else have hypogonadism?
... being sterile at 20 is quite disconcerting), but it is important to know because secondary hypogonadism is a symptom of a greater condition. There are very few conditions which cause it. Cushing's syndrome happens to be one of them.

AI Again, 2. one in 5 days
I felt my usual blah this morning, on waking at 4!!!! am. At 7 I took my 2.5 Prednisone (I had taken 5 yesterday and it made me sleep badly). At around 9 am I told my husand to get up and help with the kids. I felt too overwhelmed with ...

15 weeks post op- Cortisol and ACTH results
I never had the 5 day post op testing done, I was in the hospital and there were issues with the Endocrinologists. Anywho, I spoke with Dr F Sunday, and Thursday AM I went in for a cortisol and ACTH. I'm currently on 40mg. a day. 20/20 ...

Fractionated Radiation vs GK
...seems most everyonew here has had 1-time GK. I have been referred, after two pit surguries by an expert on oour short list, for fractionated RT...what have been the experiences here w/this protocol?

Some test results
I got the lab reports from my Endo yesterday and I am finally looking at them now. I know everyone is saying TEST, TEST, TEST but my idiot stopped me from testing and said just go to the Neurosurgeon. They were all done at Lab Corp ...

Thyroid Ultrasound
I had my Ultra sound yesterday..I had it done at my Endo the idiot's office because if I had it done at a lab I would need to wait for the results, by having the idiot do it I would have immediate results. ...

low saliva cortisol
I do have a lot of Cushings signs, but since I have such low cortisol, I must not have it, right? I have a bruise from July that hasn't entirely faded; stretch marks all over my belly; wide mood swings; severe edema. ...









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